Assay Detail
Functional
CHEMBL1794523
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PUBCHEM_BIOASSAY: Dose response confirmation of uHTS hits for small molecule modulators of myocardial damage. (Class of assay: confirmatory)
1491
Total Activities
1491
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Tissue | Myocardium |
| Cell Type | H9c2 |
| Category | confirmatory |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1491 | 4.76 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1879313 | — | — | 1 | 5.30 |
| CHEMBL1507325 | — | — | 1 | 5.30 |
| CHEMBL1497792 | — | — | 1 | 5.30 |
| CHEMBL1335812 | — | — | 1 | 5.29 |
| CHEMBL1449136 | — | — | 1 | 5.28 |
| CHEMBL1495112 | — | — | 1 | 5.23 |
| CHEMBL1727996 | — | — | 1 | 5.23 |
| CHEMBL1383978 | — | — | 1 | 5.22 |
| CHEMBL1312383 | — | — | 1 | 5.21 |
| CHEMBL1404434 | — | — | 1 | 5.20 |
| CHEMBL1557027 | — | — | 1 | 5.19 |
| CHEMBL1423148 | — | — | 1 | 5.17 |
| CHEMBL2001262 | — | — | 1 | 5.17 |
| CHEMBL1494390 | — | — | 1 | 5.17 |
| CHEMBL1730403 | — | — | 1 | 5.16 |
| CHEMBL1476641 | — | — | 1 | 5.16 |
| CHEMBL1557060 | — | — | 1 | 5.16 |
| CHEMBL1714625 | — | — | 1 | 5.15 |
| CHEMBL1415357 | — | — | 1 | 5.15 |
| CHEMBL1372064 | — | — | 1 | 5.14 |
| CHEMBL68230 | — | — | 1 | 5.14 |
| CHEMBL1302865 | — | — | 1 | 5.14 |
| CHEMBL1572906 | — | — | 1 | 5.13 |
| CHEMBL1442453 | — | — | 1 | 5.13 |
| CHEMBL1334334 | — | — | 1 | 5.12 |
| CHEMBL1719590 | — | — | 1 | 5.12 |
| CHEMBL1375247 | — | — | 1 | 5.12 |
| CHEMBL1712358 | — | — | 1 | 5.11 |
| CHEMBL1698435 | — | — | 1 | 5.11 |
| CHEMBL1986319 | — | — | 1 | 5.10 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1879313 | — | IC50 | = | 4989.0 | nM | 5.30 |
| CHEMBL1507325 | — | IC50 | = | 4958.0 | nM | 5.30 |
| CHEMBL1497792 | — | IC50 | = | 5058.0 | nM | 5.30 |
| CHEMBL1335812 | — | IC50 | = | 5136.0 | nM | 5.29 |
| CHEMBL1449136 | — | IC50 | = | 5261.0 | nM | 5.28 |
| CHEMBL1495112 | — | IC50 | = | 5877.0 | nM | 5.23 |
| CHEMBL1727996 | — | IC50 | = | 5839.0 | nM | 5.23 |
| CHEMBL1383978 | — | IC50 | = | 5988.0 | nM | 5.22 |
| CHEMBL1312383 | — | IC50 | = | 6176.0 | nM | 5.21 |
| CHEMBL1404434 | — | IC50 | = | 6287.0 | nM | 5.20 |
| CHEMBL1557027 | — | IC50 | = | 6509.0 | nM | 5.19 |
| CHEMBL1494390 | — | IC50 | = | 6724.0 | nM | 5.17 |
| CHEMBL1423148 | — | IC50 | = | 6792.0 | nM | 5.17 |
| CHEMBL2001262 | — | IC50 | = | 6720.0 | nM | 5.17 |
| CHEMBL1557060 | — | IC50 | = | 6928.0 | nM | 5.16 |
| CHEMBL1476641 | — | IC50 | = | 6989.0 | nM | 5.16 |
| CHEMBL1730403 | — | IC50 | = | 6934.0 | nM | 5.16 |
| CHEMBL1415357 | — | IC50 | = | 7040.0 | nM | 5.15 |
| CHEMBL1714625 | — | IC50 | = | 7054.0 | nM | 5.15 |
| CHEMBL68230 | — | IC50 | = | 7276.0 | nM | 5.14 |
| CHEMBL1302865 | — | IC50 | = | 7169.0 | nM | 5.14 |
| CHEMBL1372064 | — | IC50 | = | 7299.0 | nM | 5.14 |
| CHEMBL1572906 | — | IC50 | = | 7478.0 | nM | 5.13 |
| CHEMBL1442453 | — | IC50 | = | 7450.0 | nM | 5.13 |
| CHEMBL1719590 | — | IC50 | = | 7531.0 | nM | 5.12 |
| CHEMBL1375247 | — | IC50 | = | 7520.0 | nM | 5.12 |
| CHEMBL1334334 | — | IC50 | = | 7592.0 | nM | 5.12 |
| CHEMBL1712358 | — | IC50 | = | 7693.0 | nM | 5.11 |
| CHEMBL1698435 | — | IC50 | = | 7697.0 | nM | 5.11 |
| CHEMBL1986319 | — | IC50 | = | 7923.0 | nM | 5.10 |
| CHEMBL1733606 | — | IC50 | = | 8150.0 | nM | 5.09 |
| CHEMBL1332261 | — | IC50 | = | 8085.0 | nM | 5.09 |
| CHEMBL1363855 | — | IC50 | = | 8340.0 | nM | 5.08 |
| CHEMBL1982896 | — | IC50 | = | 8263.0 | nM | 5.08 |
| CHEMBL1453916 | — | IC50 | = | 8285.0 | nM | 5.08 |
| CHEMBL1453306 | — | IC50 | = | 8562.0 | nM | 5.07 |
| CHEMBL1452652 | — | IC50 | = | 8596.0 | nM | 5.07 |
| CHEMBL1735066 | — | IC50 | = | 8489.0 | nM | 5.07 |
| CHEMBL1416591 | — | IC50 | = | 8432.0 | nM | 5.07 |
| CHEMBL1547685 | — | IC50 | = | 8615.0 | nM | 5.07 |
| CHEMBL1557763 | — | IC50 | = | 8669.0 | nM | 5.06 |
| CHEMBL1553364 | — | IC50 | = | 8695.0 | nM | 5.06 |
| CHEMBL1599015 | — | IC50 | = | 8775.0 | nM | 5.06 |
| CHEMBL1416039 | — | IC50 | = | 8815.0 | nM | 5.05 |
| CHEMBL1606890 | — | IC50 | = | 8830.0 | nM | 5.05 |
| CHEMBL1364817 | — | IC50 | = | 8818.0 | nM | 5.05 |
| CHEMBL1380024 | — | IC50 | = | 8916.0 | nM | 5.05 |
| CHEMBL1575293 | — | IC50 | = | 8883.0 | nM | 5.05 |
| CHEMBL1879523 | — | IC50 | = | 8804.0 | nM | 5.05 |
| CHEMBL1900738 | — | IC50 | = | 9139.0 | nM | 5.04 |