Assay Detail
ADMET
CHEMBL1825558
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP3A4 using a fluorescent probe 7-benzyloxyquinoline
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.40 | 7.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1825089 | — | — | 1 | 7.40 |
| CHEMBL1825096 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1825089 | — | IC50 | = | 40.0 | nM | 7.40 |
| CHEMBL1825096 | — | IC50 | > | 10000.0 | nM | - |