Assay Detail
ADMET
CHEMBL1921622
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Inhibition of CYP3A4
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Aminothiazoles as γ-secretase modulators.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.79 | 5.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1915565 | — | — | 1 | 5.92 |
| CHEMBL1915566 | — | — | 1 | 5.66 |
| CHEMBL1915563 | — | — | 1 | - |
| CHEMBL1915564 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1915565 | — | IC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL1915566 | — | IC50 | = | 2200.0 | nM | 5.66 |
| CHEMBL1915563 | — | IC50 | < | 200.0 | nM | - |
| CHEMBL1915564 | — | IC50 | < | 200.0 | nM | - |