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Assay Detail

CHEMBL1937182

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cells in presence of 100 uM phenylboronic acid
2
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Cell Type HEK-293T
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Beta-2 adrenergic receptor (CHEMBL210)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Cell-based and in-silico studies on the high intrinsic activity of two boron-containing salbutamol derivatives at the human β₂-adrenoceptor.
Soriano-Ursúa MA, McNaught-Flores DA, Nieto-Alamilla G, Segura-Cabrera A, Correa-Basurto J, Arias-Montaño JA, Trujillo-Ferrara JG.
Bioorg Med Chem (2012) 20 : 933 -941
PubMed 22182578 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 5.33 5.33

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1002 LEVOSALBUTAMOL 4.0 2 5.33

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1002 LEVOSALBUTAMOL Ki = 4677.0 nM 5.33
CHEMBL1002 LEVOSALBUTAMOL Ki = 4677.35 nM 5.33