Assay Detail
Binding
CHEMBL1944115
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]mesulergine from rat 5HT2C receptor by liquid scintillation counting
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Multi-receptor drug design: Haloperidol as a scaffold for the design and synthesis of atypical antipsychotic agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 5.15 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL140872 | — | — | 1 | 5.38 |
| CHEMBL1940419 | — | — | 1 | 5.09 |
| CHEMBL1940420 | — | — | 1 | 5.08 |
| CHEMBL1940416 | — | — | 1 | 5.05 |
| CHEMBL1940403 | — | — | 1 | - |
| CHEMBL1940405 | — | — | 1 | - |
| CHEMBL1940406 | — | — | 1 | - |
| CHEMBL1940407 | — | — | 1 | - |
| CHEMBL1940417 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL140872 | — | Ki | = | 4132.0 | nM | 5.38 |
| CHEMBL1940419 | — | Ki | = | 8097.0 | nM | 5.09 |
| CHEMBL1940420 | — | Ki | = | 8277.0 | nM | 5.08 |
| CHEMBL1940416 | — | Ki | = | 8829.0 | nM | 5.05 |
| CHEMBL1940403 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1940405 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1940406 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1940407 | — | Ki | > | 10000.0 | nM | - |
| CHEMBL1940417 | — | Ki | > | 10000.0 | nM | - |