Assay Detail
Binding
CHEMBL1947814
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Binding affinity to beta1 adrenoceptor
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
From libraries to candidate: the discovery of new ultra long-acting dibasic β₂-adrenoceptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.40 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1095777 | INDACATEROL | 4.0 | 1 | 6.50 |
| CHEMBL1263 | SALMETEROL | 4.0 | 1 | 6.30 |
| CHEMBL1256786 | FORMOTEROL | 4.0 | 1 | - |
| CHEMBL82663 | SIBENADET | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1095777 | INDACATEROL | IC50 | = | 316.23 | nM | 6.50 |
| CHEMBL1263 | SALMETEROL | IC50 | = | 501.19 | nM | 6.30 |
| CHEMBL1256786 | FORMOTEROL | IC50 | > | 630.96 | nM | - |
| CHEMBL82663 | SIBENADET | IC50 | > | 10000.0 | nM | - |