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Assay Detail

CHEMBL1963717

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: STK17A
ChEMBL ↗
593
Total Activities
583
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Serine/threonine-protein kinase 17A (CHEMBL4525) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 593 6.53 8.60

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1980995 — — 1 8.60
CHEMBL1983111 — — 1 8.50
CHEMBL1984548 — — 1 8.50
CHEMBL1973540 — — 1 8.40
CHEMBL1994669 — — 1 8.20
CHEMBL1972290 — — 1 8.10
CHEMBL379975 — — 1 8.10
CHEMBL1992363 — — 1 8.10
CHEMBL1967878 CENISERTIB 2.0 1 8.10
CHEMBL1999931 — — 1 8.00
CHEMBL1966343 — — 1 7.90
CHEMBL1966204 — — 1 7.90
CHEMBL2005475 — — 1 7.90
CHEMBL1985723 — — 1 7.90
CHEMBL1990162 — — 1 7.80
CHEMBL1987261 — — 1 7.80
CHEMBL2005718 — — 1 7.80
CHEMBL1972142 — — 1 7.80
CHEMBL2001751 — — 1 7.80
CHEMBL1983945 — — 1 7.70
CHEMBL1986666 — — 1 7.70
CHEMBL1986263 — — 1 7.70
CHEMBL1965660 — — 2 7.60
CHEMBL1987448 — — 1 7.60
CHEMBL1995740 — — 1 7.60
CHEMBL244378 — — 1 7.60
CHEMBL1975500 — — 1 7.50
CHEMBL1996980 — — 1 7.50
CHEMBL2002613 — — 1 7.50
CHEMBL1998432 — — 1 7.50

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1980995 — Ki = 2.512 nM 8.60
CHEMBL1983111 — Ki = 3.162 nM 8.50
CHEMBL1984548 — Ki = 3.162 nM 8.50
CHEMBL1973540 — Ki = 3.981 nM 8.40
CHEMBL1994669 — Ki = 6.31 nM 8.20
CHEMBL1967878 CENISERTIB Ki = 7.943 nM 8.10
CHEMBL1972290 — Ki = 7.943 nM 8.10
CHEMBL379975 — Ki = 7.943 nM 8.10
CHEMBL1992363 — Ki = 7.943 nM 8.10
CHEMBL1999931 — Ki = 10.0 nM 8.00
CHEMBL2005475 — Ki = 12.59 nM 7.90
CHEMBL1985723 — Ki = 12.59 nM 7.90
CHEMBL1966204 — Ki = 12.59 nM 7.90
CHEMBL1966343 — Ki = 12.59 nM 7.90
CHEMBL1987261 — Ki = 15.85 nM 7.80
CHEMBL2001751 — Ki = 15.85 nM 7.80
CHEMBL1990162 — Ki = 15.85 nM 7.80
CHEMBL2005718 — Ki = 15.85 nM 7.80
CHEMBL1972142 — Ki = 15.85 nM 7.80
CHEMBL1986666 — Ki = 19.95 nM 7.70
CHEMBL1983945 — Ki = 19.95 nM 7.70
CHEMBL1986263 — Ki = 19.95 nM 7.70
CHEMBL1995740 — Ki = 25.12 nM 7.60
CHEMBL1987448 — Ki = 25.12 nM 7.60
CHEMBL1965660 — Ki = 25.12 nM 7.60
CHEMBL1965660 — Ki = 25.12 nM 7.60
CHEMBL244378 — Ki = 25.12 nM 7.60
CHEMBL1973720 — Ki = 31.62 nM 7.50
CHEMBL1996980 — Ki = 31.62 nM 7.50
CHEMBL243298 — Ki = 31.62 nM 7.50
CHEMBL1998432 — Ki = 31.62 nM 7.50
CHEMBL1975500 — Ki = 31.62 nM 7.50
CHEMBL2002613 — Ki = 31.62 nM 7.50
CHEMBL1966628 — Ki = 31.62 nM 7.50
CHEMBL2000832 — Ki = 31.62 nM 7.50
CHEMBL1973720 — Ki = 31.62 nM 7.50
CHEMBL1988163 — Ki = 31.62 nM 7.50
CHEMBL1976134 — Ki = 31.62 nM 7.50
CHEMBL1986943 — Ki = 39.81 nM 7.40
CHEMBL396523 — Ki = 39.81 nM 7.40
CHEMBL592030 — Ki = 39.81 nM 7.40
CHEMBL1986943 — Ki = 39.81 nM 7.40
CHEMBL1983932 — Ki = 39.81 nM 7.40
CHEMBL1725279 SP-600125 Ki = 39.81 nM 7.40
CHEMBL1976090 — Ki = 39.81 nM 7.40
CHEMBL475251 R-406 Ki = 39.81 nM 7.40
CHEMBL243088 — Ki = 39.81 nM 7.40
CHEMBL1980435 — Ki = 39.81 nM 7.40
CHEMBL1971172 — Ki = 39.81 nM 7.40
CHEMBL2007064 — Ki = 50.12 nM 7.30