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Assay Detail

CHEMBL1963813

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
PUBCHEM_BIOASSAY: Navigating the Kinome. (Class of assay: other) Panel member name: CDC2L6
ChEMBL ↗
199
Total Activities
197
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Category other
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Cyclin-dependent kinase 19 (CHEMBL6002) ↗
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

PubChem BioAssay data set

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 199 5.70 7.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1969834 — — 1 7.70
CHEMBL243088 — — 1 7.30
CHEMBL243749 — — 1 7.10
CHEMBL572878 TOZASERTIB 2.0 1 6.70
CHEMBL592030 — — 1 6.40
CHEMBL1981725 — — 1 6.30
CHEMBL2005631 — — 1 6.30
CHEMBL1090363 — — 1 6.20
CHEMBL1983634 — — 1 6.00
CHEMBL1973937 — — 1 6.00
CHEMBL1966722 — — 1 6.00
CHEMBL1967998 — — 1 6.00
CHEMBL1973893 — — 1 6.00
CHEMBL374044 — — 1 5.70
CHEMBL2005828 — — 1 5.70
CHEMBL1982135 — — 1 5.70
CHEMBL220057 — — 1 5.70
CHEMBL1991999 — — 1 5.70
CHEMBL3145328 — — 1 5.70
CHEMBL1993073 — — 1 5.70
CHEMBL1976878 — — 1 5.70
CHEMBL2004033 — — 1 5.50
CHEMBL2001239 — — 1 5.50
CHEMBL2000832 — — 1 5.50
CHEMBL1974090 — — 1 5.50
CHEMBL1995740 — — 1 5.50
CHEMBL1974803 — — 1 5.50
CHEMBL1964687 — — 1 5.50
CHEMBL1995068 — — 1 5.40
CHEMBL482767 SNS-314 1.0 1 5.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1969834 — Ki = 19.95 nM 7.70
CHEMBL243088 — Ki = 50.12 nM 7.30
CHEMBL243749 — Ki = 79.43 nM 7.10
CHEMBL572878 TOZASERTIB Ki = 199.53 nM 6.70
CHEMBL592030 — Ki = 398.11 nM 6.40
CHEMBL1981725 — Ki = 501.19 nM 6.30
CHEMBL2005631 — Ki = 501.19 nM 6.30
CHEMBL1090363 — Ki = 630.96 nM 6.20
CHEMBL1973893 — Ki = 1000.0 nM 6.00
CHEMBL1967998 — Ki = 1000.0 nM 6.00
CHEMBL1973937 — Ki = 1000.0 nM 6.00
CHEMBL1983634 — Ki = 1000.0 nM 6.00
CHEMBL1966722 — Ki = 1000.0 nM 6.00
CHEMBL220057 — Ki = 1995.26 nM 5.70
CHEMBL1993073 — Ki = 1995.26 nM 5.70
CHEMBL2005828 — Ki = 1995.26 nM 5.70
CHEMBL3145328 — Ki = 1995.26 nM 5.70
CHEMBL374044 — Ki = 1995.26 nM 5.70
CHEMBL1976878 — Ki = 1995.26 nM 5.70
CHEMBL1982135 — Ki = 1995.26 nM 5.70
CHEMBL1991999 — Ki = 1995.26 nM 5.70
CHEMBL1995740 — Ki = 3162.28 nM 5.50
CHEMBL1974090 — Ki = 3162.28 nM 5.50
CHEMBL1964687 — Ki = 3162.28 nM 5.50
CHEMBL2000832 — Ki = 3162.28 nM 5.50
CHEMBL2001239 — Ki = 3162.28 nM 5.50
CHEMBL2004033 — Ki = 3162.28 nM 5.50
CHEMBL1974803 — Ki = 3162.28 nM 5.50
CHEMBL1968406 — Ki = 3981.07 nM 5.40
CHEMBL482767 SNS-314 Ki = 3981.07 nM 5.40
CHEMBL1995068 — Ki = 3981.07 nM 5.40
CHEMBL1965507 — Ki = 3981.07 nM 5.40
CHEMBL1983106 — Ki = 5011.87 nM 5.30
CHEMBL2005953 — Ki = 6309.57 nM 5.20
CHEMBL1983875 — Ki = 6309.57 nM 5.20
CHEMBL50894 ALSTERPAULLONE Ki = 10000.0 nM 5.00
CHEMBL1987104 — Ki = 10000.0 nM 5.00
CHEMBL184847 — Ki = 19952.62 nM 4.70
CHEMBL33891 — Ki = 19952.62 nM 4.70
CHEMBL1987881 — Ki = 31622.78 nM 4.50
CHEMBL2004892 — Ki = 63095.73 nM 4.20
CHEMBL183844 — Ki > 100000.0 nM -
CHEMBL2006715 — Ki > 100000.0 nM -
CHEMBL1393571 — Ki > 100000.0 nM -
CHEMBL2005475 — Ki > 100000.0 nM -
CHEMBL2002450 — Ki > 100000.0 nM -
CHEMBL1970083 — Ki > 100000.0 nM -
CHEMBL1978099 — Ki > 100000.0 nM -
CHEMBL1983534 — Ki > 100000.0 nM -
CHEMBL1976134 — Ki > 100000.0 nM -