Assay Detail
Binding
CHEMBL2019478
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Displacement of [3H]oxytocin from human oxytocin receptor after 1.5 hrs by liquid scintillation counting
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and evaluation of C-11, F-18 and I-125 small molecule radioligands for detecting oxytocin receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 7.74 | 8.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2017868 | — | — | 1 | 8.24 |
| CHEMBL2017867 | — | — | 1 | 8.00 |
| CHEMBL2017869 | — | — | 1 | 7.80 |
| CHEMBL2017979 | — | — | 1 | 7.55 |
| CHEMBL2017980 | — | — | 1 | 7.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2017868 | — | Ki | = | 5.7 | nM | 8.24 |
| CHEMBL2017867 | — | Ki | = | 10.0 | nM | 8.00 |
| CHEMBL2017869 | — | Ki | = | 16.0 | nM | 7.80 |
| CHEMBL2017979 | — | Ki | = | 28.0 | nM | 7.55 |
| CHEMBL2017980 | — | Ki | = | 78.0 | nM | 7.11 |