Assay Detail
Functional
CHEMBL2049997
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Cytotoxicity against human A2780 cells after 5 days by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and study of cyclic pronucleotides of 5-fluoro-2'-deoxyuridine.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.23 | 7.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL917 | FLOXURIDINE | 4.0 | 1 | 7.58 |
| CHEMBL2046835 | — | — | 1 | 6.26 |
| CHEMBL2046833 | — | — | 1 | 5.85 |
| CHEMBL2046834 | — | — | 1 | 5.85 |
| CHEMBL2046836 | — | — | 1 | 5.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL917 | FLOXURIDINE | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL2046835 | — | IC50 | = | 550.0 | nM | 6.26 |
| CHEMBL2046833 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL2046834 | — | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL2046836 | — | IC50 | = | 2400.0 | nM | 5.62 |