Assay Detail
Toxicity
CHEMBL2072334
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Toxicity against mouse RAW264.7 cells by XTT assay
13
Total Activities
13
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Toxicity |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Leishmanicidal activities and cytotoxicities of bisnaphthoquinone analogues and naphthol derivatives from Burman Diospyros burmanica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 13 | 4.73 | 6.20 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL64925 | MG-132 | — | 1 | 6.20 |
| CHEMBL2071223 | BURMANIN C | — | 1 | 4.66 |
| CHEMBL2071225 | BURMANIN A | — | 1 | 4.62 |
| CHEMBL2071226 | BURMANIN B | — | 1 | 4.51 |
| CHEMBL1531003 | — | — | 1 | 4.35 |
| CHEMBL2071233 | — | — | 1 | 4.02 |
| CHEMBL2071224 | — | — | 1 | - |
| CHEMBL2071227 | — | — | 1 | - |
| CHEMBL2071228 | — | — | 1 | - |
| CHEMBL2071229 | — | — | 1 | - |
| CHEMBL2071230 | — | — | 1 | - |
| CHEMBL2071231 | — | — | 1 | - |
| CHEMBL2071232 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL64925 | MG-132 | IC50 | = | 630.0 | nM | 6.20 |
| CHEMBL2071223 | BURMANIN C | IC50 | = | 22000.0 | nM | 4.66 |
| CHEMBL2071225 | BURMANIN A | IC50 | = | 24000.0 | nM | 4.62 |
| CHEMBL2071226 | BURMANIN B | IC50 | = | 31000.0 | nM | 4.51 |
| CHEMBL1531003 | — | IC50 | = | 45000.0 | nM | 4.35 |
| CHEMBL2071233 | — | IC50 | = | 96000.0 | nM | 4.02 |
| CHEMBL2071224 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2071227 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2071228 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2071229 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2071230 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2071231 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL2071232 | — | IC50 | > | 100000.0 | nM | - |