Assay Detail
Functional
CHEMBL2078221
Review assay metadata, readout intent, target linkage, and publication context from the same page.
TP_TRANSPORTER: inhibition of Taurocholate uptake in canalicular membrane vesicles of rat liver
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Liver |
| Subcellular | Canalicular membrane vesicle |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Inhibition of transport across the hepatocyte canalicular membrane by the antibiotic fusidate.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 5.66 | 5.66 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL374975 | FUSIDIC ACID | 3.0 | 1 | 5.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL374975 | FUSIDIC ACID | Ki | = | 2200.0 | nM | 5.66 |