Assay Detail
Functional
CHEMBL2114714
Review assay metadata, readout intent, target linkage, and publication context from the same page.
PubChem BioAssay. Dose Response Confirmation of SKN-1 Inhibitor hits in a fluorescence ratio assay. (Class of assay: confirmatory)
1381
Total Activities
1380
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Category | confirmatory |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
PubChem BioAssay data set
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1381 | 4.52 | 5.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1530862 | — | — | 1 | 5.50 |
| CHEMBL1575487 | — | — | 1 | 5.48 |
| CHEMBL1899739 | — | — | 1 | 5.46 |
| CHEMBL1880991 | — | — | 1 | 5.43 |
| CHEMBL1416100 | — | — | 1 | 5.39 |
| CHEMBL1531150 | — | — | 1 | 5.38 |
| CHEMBL1706710 | — | — | 1 | 5.37 |
| CHEMBL1607514 | — | — | 1 | 5.36 |
| CHEMBL1462983 | — | — | 1 | 5.35 |
| CHEMBL1866688 | — | — | 1 | 5.33 |
| CHEMBL1467579 | — | — | 1 | 5.32 |
| CHEMBL1731096 | — | — | 1 | 5.32 |
| CHEMBL1519452 | — | — | 1 | 5.25 |
| CHEMBL1711260 | — | — | 1 | 5.24 |
| CHEMBL1449896 | — | — | 1 | 5.22 |
| CHEMBL1532349 | — | — | 1 | 5.21 |
| CHEMBL1523365 | — | — | 1 | 5.21 |
| CHEMBL1467262 | — | — | 1 | 5.20 |
| CHEMBL1712668 | — | — | 1 | 5.20 |
| CHEMBL1347974 | — | — | 1 | 5.18 |
| CHEMBL1608954 | — | — | 1 | 5.17 |
| CHEMBL1463767 | — | — | 1 | 5.16 |
| CHEMBL1335915 | — | — | 1 | 5.11 |
| CHEMBL1359529 | — | — | 1 | 5.10 |
| CHEMBL1343697 | — | — | 1 | 5.10 |
| CHEMBL1608480 | — | — | 1 | 5.10 |
| CHEMBL1604614 | — | — | 1 | 5.06 |
| CHEMBL1493429 | — | — | 1 | 5.04 |
| CHEMBL1511924 | — | — | 1 | 5.03 |
| CHEMBL1723862 | — | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1530862 | — | IC50 | = | 3180.0 | nM | 5.50 |
| CHEMBL1575487 | — | IC50 | = | 3330.0 | nM | 5.48 |
| CHEMBL1899739 | — | IC50 | = | 3460.0 | nM | 5.46 |
| CHEMBL1880991 | — | IC50 | = | 3750.0 | nM | 5.43 |
| CHEMBL1416100 | — | IC50 | = | 4050.0 | nM | 5.39 |
| CHEMBL1531150 | — | IC50 | = | 4150.0 | nM | 5.38 |
| CHEMBL1706710 | — | IC50 | = | 4240.0 | nM | 5.37 |
| CHEMBL1607514 | — | IC50 | = | 4340.0 | nM | 5.36 |
| CHEMBL1462983 | — | IC50 | = | 4450.0 | nM | 5.35 |
| CHEMBL1866688 | — | IC50 | = | 4620.0 | nM | 5.33 |
| CHEMBL1731096 | — | IC50 | = | 4770.0 | nM | 5.32 |
| CHEMBL1467579 | — | IC50 | = | 4740.0 | nM | 5.32 |
| CHEMBL1519452 | — | IC50 | = | 5670.0 | nM | 5.25 |
| CHEMBL1711260 | — | IC50 | = | 5710.0 | nM | 5.24 |
| CHEMBL1449896 | — | IC50 | = | 5970.0 | nM | 5.22 |
| CHEMBL1523365 | — | IC50 | = | 6090.0 | nM | 5.21 |
| CHEMBL1532349 | — | IC50 | = | 6110.0 | nM | 5.21 |
| CHEMBL1467262 | — | IC50 | = | 6330.0 | nM | 5.20 |
| CHEMBL1712668 | — | IC50 | = | 6360.0 | nM | 5.20 |
| CHEMBL1347974 | — | IC50 | = | 6560.0 | nM | 5.18 |
| CHEMBL1608954 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL1463767 | — | IC50 | = | 6860.0 | nM | 5.16 |
| CHEMBL1335915 | — | IC50 | = | 7700.0 | nM | 5.11 |
| CHEMBL1359529 | — | IC50 | = | 7910.0 | nM | 5.10 |
| CHEMBL1343697 | — | IC50 | = | 7870.0 | nM | 5.10 |
| CHEMBL1608480 | — | IC50 | = | 7910.0 | nM | 5.10 |
| CHEMBL1604614 | — | IC50 | = | 8760.0 | nM | 5.06 |
| CHEMBL1493429 | — | IC50 | = | 9190.0 | nM | 5.04 |
| CHEMBL1723862 | — | IC50 | = | 9380.0 | nM | 5.03 |
| CHEMBL1511924 | — | IC50 | = | 9410.0 | nM | 5.03 |
| CHEMBL1466997 | — | IC50 | = | 9690.0 | nM | 5.01 |
| CHEMBL1610263 | — | IC50 | = | 10100.0 | nM | 5.00 |
| CHEMBL1453510 | — | IC50 | = | 10200.0 | nM | 4.99 |
| CHEMBL1477304 | — | IC50 | = | 10300.0 | nM | 4.99 |
| CHEMBL1363917 | — | IC50 | = | 10400.0 | nM | 4.98 |
| CHEMBL1403349 | — | IC50 | = | 10500.0 | nM | 4.98 |
| CHEMBL1495889 | — | IC50 | = | 10600.0 | nM | 4.97 |
| CHEMBL1611003 | — | IC50 | = | 10800.0 | nM | 4.97 |
| CHEMBL1727324 | — | IC50 | = | 10900.0 | nM | 4.96 |
| CHEMBL1402420 | PIFEXOLE | IC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL1446106 | — | IC50 | = | 11400.0 | nM | 4.94 |
| CHEMBL17201 | — | IC50 | = | 11600.0 | nM | 4.94 |
| CHEMBL1543194 | — | IC50 | = | 11400.0 | nM | 4.94 |
| CHEMBL1523565 | — | IC50 | = | 11900.0 | nM | 4.92 |
| CHEMBL1509727 | — | IC50 | = | 12200.0 | nM | 4.91 |
| CHEMBL1713227 | — | IC50 | = | 12400.0 | nM | 4.91 |
| CHEMBL1504620 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL1544408 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL1417740 | — | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL1409219 | — | IC50 | = | 12500.0 | nM | 4.90 |