Assay Detail
Functional
CHEMBL2156202
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Cytotoxicity against human A2780 cells after 96 hrs by SRB assay
14
Total Activities
14
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antitumor activity of ring A modified glycyrrhetinic acid derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 14 | 5.14 | 5.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2151608 | — | — | 1 | 5.48 |
| CHEMBL2151607 | — | — | 1 | 5.47 |
| CHEMBL2151609 | — | — | 1 | 5.27 |
| CHEMBL2151046 | — | — | 1 | 5.23 |
| CHEMBL2151610 | — | — | 1 | 5.21 |
| CHEMBL2151613 | — | — | 1 | 4.92 |
| CHEMBL2151727 | — | — | 1 | 4.82 |
| CHEMBL2151612 | — | — | 1 | 4.71 |
| CHEMBL1807165 | — | — | 1 | - |
| CHEMBL2151606 | — | — | 1 | - |
| CHEMBL2151611 | — | — | 1 | - |
| CHEMBL2151726 | — | — | 1 | - |
| CHEMBL2151728 | — | — | 1 | - |
| CHEMBL2151729 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2151608 | — | IC50 | = | 3320.0 | nM | 5.48 |
| CHEMBL2151607 | — | IC50 | = | 3420.0 | nM | 5.47 |
| CHEMBL2151609 | — | IC50 | = | 5390.0 | nM | 5.27 |
| CHEMBL2151046 | — | IC50 | = | 5890.0 | nM | 5.23 |
| CHEMBL2151610 | — | IC50 | = | 6180.0 | nM | 5.21 |
| CHEMBL2151613 | — | IC50 | = | 12030.0 | nM | 4.92 |
| CHEMBL2151727 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL2151612 | — | IC50 | = | 19730.0 | nM | 4.71 |
| CHEMBL1807165 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2151606 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2151611 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2151726 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2151728 | — | IC50 | > | 30000.0 | nM | - |
| CHEMBL2151729 | — | IC50 | > | 30000.0 | nM | - |