Assay Detail
Binding
CHEMBL2168422
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activation of human alpha1beta2gamma2L GABA A receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced current response by two-electrode voltage clamp assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | Oocyte |
| Confidence | 7 — Homologous single protein target |
| Curated By | Autocuration |
Target
GABA-A receptor; alpha-1/beta-2/gamma-2 (CHEMBL2095172) ↗| Type | PROTEIN COMPLEX |
| Organism | Homo sapiens |
Publication
Allyl m-trifluoromethyldiazirine mephobarbital: an unusually potent enantioselective and photoreactive barbiturate general anesthetic.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Imax | 1 | - | - |
| EC50 | 1 | 5.68 | 5.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2163548 | — | — | 2 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2163548 | — | EC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL2163548 | — | Imax | = | 23.0 | % | - |