Assay Detail
Functional
CHEMBL2174642
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human DU145 cells measured on day 7 by MTT assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis, and evaluation of pH-dependent hydrolyzable emetine analogues as treatment for prostate cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| IC50 | 1 | 7.62 | 7.62 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL493439 | EMETINE HYDROCHLORIDE | 2.0 | 2 | 7.62 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL493439 | EMETINE HYDROCHLORIDE | IC50 | = | 23.74 | nM | 7.62 |
| CHEMBL493439 | EMETINE HYDROCHLORIDE | Activity | - | — | - |