Assay Detail
ADMET
CHEMBL2176191
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Inhibition of CYP3A4
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Novel β-amino acid derivatives as inhibitors of cathepsin A.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 7.66 | 7.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2171398 | — | — | 1 | 7.82 |
| CHEMBL2171397 | — | — | 1 | 7.82 |
| CHEMBL2171396 | — | — | 1 | 7.58 |
| CHEMBL3145341 | — | — | 1 | 7.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2171398 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL2171397 | — | IC50 | = | 15.0 | nM | 7.82 |
| CHEMBL2171396 | — | IC50 | = | 26.0 | nM | 7.58 |
| CHEMBL3145341 | — | IC50 | = | 38.0 | nM | 7.42 |