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Assay Detail

CHEMBL2185928

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of PDGFRbeta
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

Platelet-derived growth factor receptor beta (CHEMBL1913)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Vascular endothelial growth factor (VEGF) receptors: drugs and new inhibitors.
Musumeci F, Radi M, Brullo C, Schenone S.
J Med Chem (2012) 55 : 10797 -10822
PubMed 23098265 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.16 7.16

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL352308 1 7.16

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL352308 IC50 = 69.0 nM 7.16