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Assay Detail

CHEMBL2186107

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Binding
Binding affinity to EBP
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase (CHEMBL4931)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

New positron emission tomography (PET) radioligand for imaging σ-1 receptors in living subjects.
James ML, Shen B, Zavaleta CL, Nielsen CH, Mesangeau C, Vuppala PK, Chan C, Avery BA, Fishback JA, Matsumoto RR, Gambhir SS, McCurdy CR, Chin FT.
J Med Chem (2012) 55 : 8272 -8282
PubMed 22853801 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.77 8.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2311153 1 8.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2311153 Ki = 1.7 nM 8.77