Assay Detail

CHEMBL2317167

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Functional

Antiproliferative activity against human T47D cells after 5 days by MTT assay

ChEMBL ↗

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Target

T47D (CHEMBL614361) ↗

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T47D (CHEMBL614361) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target T47D

CHEMBL614361

Anchored from Assay target.

Protein identity T47D

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	T47D
Confidence	1 — Organism
Curated By	Autocuration

Target

T47D (CHEMBL614361) ↗

Type	CELL-LINE
Organism	Homo sapiens

Publication

Antiproliferative and apoptotic effects of the oxidative dimerization product of methyl caffeate on human breast cancer cells.

Bailly F, Toillon RA, Tomavo O, Jouy N, Hondermarck H, Cotelle P.
Bioorg Med Chem Lett (2013) 23 : 574 -578
PubMed 23228470 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	8.70	8.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL145	CAFFEIC ACID	3.0	1	8.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL145	CAFFEIC ACID	IC50	=	2.0	nM	8.70