Assay Detail
Binding
CHEMBL2317642
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Binding affinity to rat GluA3-LBD (GluK3-S1S2)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chemoenzymatic synthesis of new 2,4-syn-functionalized (S)-glutamate analogues and structure-activity relationship studies at ionotropic glutamate receptors and excitatory amino acid transporters.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 5.52 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2312403 | — | — | 1 | 6.05 |
| CHEMBL384474 | — | — | 1 | 5.38 |
| CHEMBL575060 | GLUTAMIC ACID | 3.0 | 1 | 5.13 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2312403 | — | Ki | = | 900.0 | nM | 6.05 |
| CHEMBL384474 | — | Ki | = | 4200.0 | nM | 5.38 |
| CHEMBL575060 | GLUTAMIC ACID | Ki | = | 7400.0 | nM | 5.13 |