Assay Detail
Functional
CHEMBL2320853
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Antiviral activity against Guanarito virus
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Guanarito virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole and related heterocycles.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 8.64 | 9.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2314859 | — | — | 1 | 9.36 |
| CHEMBL2315146 | — | — | 1 | 8.46 |
| CHEMBL2315147 | — | — | 1 | 8.11 |
| CHEMBL2315140 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2314859 | — | EC50 | = | 0.44 | nM | 9.36 |
| CHEMBL2315146 | — | EC50 | = | 3.5 | nM | 8.46 |
| CHEMBL2315147 | — | EC50 | = | 7.7 | nM | 8.11 |
| CHEMBL2315140 | — | EC50 | - | — | - |