Assay Detail
Binding
CHEMBL2328062
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human beta-casein/APC-R3 interaction after 1 hr by alphascreen assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Adenomatous polyposis coli protein/Transcription factor 7-like 2 (CHEMBL3885511) ↗| Type | PROTEIN-PROTEIN INTERACTION |
| Organism | Homo sapiens |
Publication
High-Throughput Selectivity Assays for Small-Molecule Inhibitors of β-Catenin/T-Cell Factor Protein-Protein Interactions.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 4.47 | 5.08 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2323033 | — | — | 1 | 5.08 |
| CHEMBL578512 | — | — | 1 | 4.18 |
| CHEMBL2323029 | — | — | 1 | 4.15 |
| CHEMBL2323028 | — | — | 1 | - |
| CHEMBL2323030 | — | — | 1 | - |
| CHEMBL2323031 | — | — | 1 | - |
| CHEMBL2323032 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2323033 | — | Ki | = | 8300.0 | nM | 5.08 |
| CHEMBL578512 | — | Ki | = | 66000.0 | nM | 4.18 |
| CHEMBL2323029 | — | Ki | = | 71000.0 | nM | 4.15 |
| CHEMBL2323028 | — | Ki | = | 110000.0 | nM | - |
| CHEMBL2323030 | — | Ki | = | 110000.0 | nM | - |
| CHEMBL2323031 | — | Ki | = | 220000.0 | nM | - |
| CHEMBL2323032 | — | Ki | = | 170000.0 | nM | - |