Assay Detail
Functional
CHEMBL2328232
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Antiviral activity against Junin virus pseudovirions infected in HEK293T/17 cells after 72 hrs by luciferase reporter gene assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mammarenavirus juninense |
| Cell Type | HEK-293T |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 4 | 8.36 | 9.21 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2314859 | — | — | 1 | 9.21 |
| CHEMBL2322820 | — | — | 1 | 8.30 |
| CHEMBL2322826 | — | — | 1 | 8.11 |
| CHEMBL2322822 | — | — | 1 | 7.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2314859 | — | EC50 | = | 0.62 | nM | 9.21 |
| CHEMBL2322820 | — | EC50 | = | 5.0 | nM | 8.30 |
| CHEMBL2322826 | — | EC50 | = | 7.7 | nM | 8.11 |
| CHEMBL2322822 | — | EC50 | = | 16.0 | nM | 7.80 |