Assay Detail
Functional
CHEMBL2340756
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Cytotoxicity against human HeLaS3 cells after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa S3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Apoptosis-inducing activity of the actin-depolymerizing agent aplyronine A and its side-chain derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.41 | 9.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL412190 | APLYRONINE A | — | 1 | 9.54 |
| CHEMBL2337633 | MYCALOLIDE B | — | 1 | 7.28 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL412190 | APLYRONINE A | IC50 | = | 0.29 | nM | 9.54 |
| CHEMBL2337633 | MYCALOLIDE B | IC50 | = | 52.0 | nM | 7.28 |