Assay Detail
Binding
CHEMBL2346138
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to beta1 adrenergic receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Structure-based fragment screening is demonstrated to be a practical lead discovery method for a representative G-protein-coupled receptor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.92 | 7.17 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL200234 | — | — | 1 | 7.17 |
| CHEMBL1559535 | — | — | 1 | 6.66 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL200234 | — | Ki | = | 68.0 | nM | 7.17 |
| CHEMBL1559535 | — | Ki | = | 220.0 | nM | 6.66 |