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Assay Detail

CHEMBL2390780

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Binding
Binding affinity to mu opioid receptor (unknown origin)
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Mu-type opioid receptor (CHEMBL233)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Probes for narcotic receptor mediated phenomena. 47. Novel C4a- and N-substituted-1,2,3,4,4a,9a-hexahydrobenzofuro[2,3-c]pyridin-6-ols.
Iyer MR, Rothman RB, Dersch CM, Jacobson AE, Rice KC.
Bioorg Med Chem (2013) 21 : 3298 -3309
PubMed 23618710 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 8.73 9.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL72180 1 9.05
CHEMBL1196093 1 8.40

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL72180 Ki = 0.9 nM 9.05
CHEMBL1196093 Ki = 4.0 nM 8.40