Assay Detail
Binding
CHEMBL2394460
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Binding affinity to SARS coronavirus 3C-like protease by SPR analysis
3
Total Activities
2
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Severe acute respiratory syndrome-related coronavirus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Replicase polyprotein 1ab (CHEMBL5118) ↗| Type | SINGLE PROTEIN |
| Organism | Severe acute respiratory syndrome-related coronavirus |
Publication
Dieckol, a SARS-CoV 3CL(pro) inhibitor, isolated from the edible brown algae Ecklonia cava.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 4.80 | 4.99 |
| Activity | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL508791 | DIECKOL | — | 2 | 4.99 |
| CHEMBL399121 | HESPERETIN | 0.5 | 1 | 4.61 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL508791 | DIECKOL | Kd | = | 10300.0 | nM | 4.99 |
| CHEMBL399121 | HESPERETIN | Kd | = | 24500.0 | nM | 4.61 |
| CHEMBL508791 | DIECKOL | Activity | - | — | - |