Assay Detail
Binding
CHEMBL2406826
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of ovine COX-1 assessed as using arachidonic acid as substrate preincubated for 5 mins prior to substrate addition measured after 2 hrs by enzyme immunoassay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Ovis aries |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Stereoselective synthesis and anti-proliferative effects on prostate cancer evaluation of 5-substituted-3,4-diphenylfuran-2-ones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.22 | 5.51 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2403527 | — | — | 1 | 5.51 |
| CHEMBL2403537 | — | — | 1 | 5.09 |
| CHEMBL2403600 | — | — | 1 | 5.07 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2403527 | — | IC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL2403537 | — | IC50 | = | 8200.0 | nM | 5.09 |
| CHEMBL2403600 | — | IC50 | = | 8500.0 | nM | 5.07 |