Assay Detail
Functional
CHEMBL2416952
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Cytotoxicity against human A2780 cells after 72 hrs by MTT assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | A2780 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
A convenient synthesis of lubeluzole and its enantiomer: evaluation as chemosensitizing agents on human ovarian adenocarcinoma and lung carcinoma cells.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.91 | 7.64 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 7.64 |
| CHEMBL281724 | LUBELUZOLE | 2.0 | 1 | 5.24 |
| CHEMBL338327 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL281724 | LUBELUZOLE | IC50 | = | 5700.0 | nM | 5.24 |
| CHEMBL338327 | — | IC50 | = | 14000.0 | nM | 4.85 |