Assay Detail

CHEMBL2433152

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Antimicrobial activity against Plasmodium

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Open DB target context

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NON-PROTEIN TARGET (CHEMBL3879801) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Plasmodium
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Cell-based medicinal chemistry optimization of high-throughput screening (HTS) hits for orally active antimalarials. Part 1: challenges in potency and absorption, distribution, metabolism, excretion/pharmacokinetics (ADME/PK).

Chatterjee AK.
J Med Chem (2013) 56 : 7741 -7749
PubMed 23927720 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
EC50	1	4.70	4.70

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL446918	CLOPIDOL	2.0	1	4.70

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL446918	CLOPIDOL	EC50	=	20000.0	nM	4.70