Assay Detail
Binding
CHEMBL2437600
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]LY278584 from mouse 5-HT3A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
2-Amino-6-chloro-3,4-dihydroquinazoline: A novel 5-HT3 receptor antagonist with antidepressant character.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 6.40 | 7.10 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2436555 | — | — | 1 | 7.10 |
| CHEMBL2436556 | — | — | 1 | 5.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2436555 | — | Ki | = | 80.0 | nM | 7.10 |
| CHEMBL2436556 | — | Ki | = | 1975.0 | nM | 5.70 |