Compound Detail
CHEMBL2436556
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2436556 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DRRYBJKRHULBHY-UHFFFAOYSA-N |
| Parent Compound | CHEMBL13864 |
| Active Moiety | CHEMBL13864 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
181.6
MW (Da)
1.39
ALogP
3
HBA
2
HBD
50.4
PSA (Ų)
0.64
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 3A CHEMBL4972 | Ki | 5.7 | 5.7 | 1975.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 3A | Ki | = | 1975.0 | nM | 5.7 | Displacement of [3H]LY278584 from mouse 5-HT3A receptor | 24035337 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24035337 | 10.1016/j.bmcl.2013.08.072 | 5-hydroxytryptamine receptor 3A | 1 |
Data from ChEMBL 36 via Core Engine