Assay Detail
Functional
CHEMBL2439007
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Cytotoxicity against mouse P388 cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | P388 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel 1H-pyrrolo[2,3-b]pyridine derivative nortopsentin analogues: synthesis and antitumor activity in peritoneal mesothelioma experimental models.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.35 | 5.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL63208 | NORTOPSENTIN C | — | 1 | 5.35 |
| CHEMBL302637 | NORTOPSENTIN A | — | 1 | 5.35 |
| CHEMBL292801 | NORTOPSENTIN B | — | 1 | 5.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL63208 | NORTOPSENTIN C | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL302637 | NORTOPSENTIN A | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL292801 | NORTOPSENTIN B | IC50 | = | 4500.0 | nM | 5.35 |