Assay Detail

CHEMBL3056707

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional

Inhibition of free-radical-induced lipid peroxidation in Rattus norvegicus (rat) brain homogenates

ChEMBL ↗

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Target

Brain (CHEMBL613617) ↗

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Primary target Brain

CHEMBL613617

Anchored from Assay target.

Protein identity Brain

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Rattus norvegicus
Tissue	Brain
Confidence	1 — Organism
Curated By	Autocuration

Target

Brain (CHEMBL613617) ↗

Type	TISSUE
Organism	Rattus norvegicus

Publication

Transition metals in organic synthesis - Part 83#: Synthesis and pharmacological potential of carbazoles

Choi TA, Czerwonka R, Forke R, Jager A, Knoll J, Krahl MP, Krause T, Reddy KR, Franzblau SG, Knolker H
Med Chem Res (2008) 17 : 374 -385
· DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	6.41	6.41

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL2260665	(R)-(-)-NEOCARAZOSTATIN B	—	1	6.41

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL2260665	(R)-(-)-NEOCARAZOSTATIN B	IC50	=	390.0	nM	6.41