Compound Detail
CHEMBL2260665
(R)-(-)-NEOCARAZOSTATIN B Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2260665 |
| Name | (R)-(-)-NEOCARAZOSTATIN B |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SDXRDEAECLPZHL-CYBMUJFWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
353.5
MW (Da)
4.78
ALogP
3
HBA
3
HBD
65.5
PSA (Ų)
0.58
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.41
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Brain CHEMBL613617 | IC50 | 6.41 | 6.41 | 390.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Brain | IC50 | = | 390.0 | nM | 6.41 | Inhibition of free-radical-induced lipid peroxidation in Rattus norvegicus (rat)... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1007/s00044-007-9073-0 | Brain | 1 |
| 28094223 | 10.1016/j.bmc.2016.12.038 | Vero | 1 |
| 28094223 | 10.1016/j.bmc.2016.12.038 | Mycobacterium tuberculosis | 1 |
Data from ChEMBL 36 via Core Engine