Assay Detail
Binding
CHEMBL3073098
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]quinpirole from high affinity agonist binding site of D2 receptor in Rattus norvegicus (rat) striatal membrane
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Striatum |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Action of benzimidazolo-piperazinyl derivatives on dopamine receptors
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 9 | 8.28 | 9.29 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2298812 | — | — | 1 | 9.29 |
| CHEMBL314952 | — | — | 1 | 9.25 |
| CHEMBL2298808 | — | — | 1 | 8.49 |
| CHEMBL315864 | — | — | 1 | 8.38 |
| CHEMBL88365 | — | — | 1 | 8.26 |
| CHEMBL2298810 | — | — | 1 | 8.04 |
| CHEMBL2298811 | — | — | 1 | 8.01 |
| CHEMBL2298809 | — | — | 1 | 7.57 |
| CHEMBL330108 | — | — | 1 | 7.26 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2298812 | — | Ki | = | 0.51 | nM | 9.29 |
| CHEMBL314952 | — | Ki | = | 0.56 | nM | 9.25 |
| CHEMBL2298808 | — | Ki | = | 3.2 | nM | 8.49 |
| CHEMBL315864 | — | Ki | = | 4.2 | nM | 8.38 |
| CHEMBL88365 | — | Ki | = | 5.5 | nM | 8.26 |
| CHEMBL2298810 | — | Ki | = | 9.1 | nM | 8.04 |
| CHEMBL2298811 | — | Ki | = | 9.7 | nM | 8.01 |
| CHEMBL2298809 | — | Ki | = | 26.8 | nM | 7.57 |
| CHEMBL330108 | — | Ki | = | 54.8 | nM | 7.26 |