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Assay Detail

CHEMBL3073347

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of photosystem II in s-triazine-resistant Poa annua leaf thylakoid membrane assessed as reduction of photosynthetic electron transport
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Poa annua
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Photosystem Q(B) protein (CHEMBL2366557)
Type SINGLE PROTEIN
Organism Poa annua

Publication

Molecular Basis of Resistance to s-Triazine Herbicides in Poa annua L. and Its Photosynthetic Properties under Different Light Conditions
KUMATA S, YONEYAMA K, OGASAWARA M, TAKEUCHI Y, KONNAI M, NAKAJIMA Y, NAKANO T, YOSHIDA S
J Pestic Sci (2001) 26 : 236 -243
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 4 5.83 6.40

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1892987 DINOSEB 1 6.40
CHEMBL278489 DCMU 1 6.40
CHEMBL1522462 LENACIL 1 4.70
CHEMBL15063 ATRAZINE 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1892987 DINOSEB IC50 = 400.0 nM 6.40
CHEMBL278489 DCMU IC50 = 400.0 nM 6.40
CHEMBL1522462 LENACIL IC50 = 20000.0 nM 4.70
CHEMBL15063 ATRAZINE IC50 > 100000.0 nM -