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Assay Detail

CHEMBL3080028

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Inhibition of colored carotenoid formation in Nicotiana tabacum (tobacco)
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Nicotiana tabacum
Confidence 1 — Organism
Curated By Autocuration

Target

Nicotiana tabacum (CHEMBL613059)
Type ORGANISM
Organism Nicotiana tabacum

Publication

Mode of Action of Herbicides Affecting Carotenogenesis
BOGER P
J Pestic Sci (1996) 21 : 473 -478
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 9 6.42 7.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL2286104 FLURIDONE 1 7.64
CHEMBL1425995 DIFLUFENICAN 1 7.42
CHEMBL2271108 1 7.38
CHEMBL1863061 FLURTAMONE 1 7.33
CHEMBL1881194 NORFLURAZONE 1 6.48
CHEMBL2286103 1 6.13
CHEMBL2286102 1 5.89
CHEMBL2272974 1 5.35
CHEMBL232801 AMITROLE 1 4.17

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL2286104 FLURIDONE IC50 = 23.0 nM 7.64
CHEMBL1425995 DIFLUFENICAN IC50 = 38.0 nM 7.42
CHEMBL2271108 IC50 = 42.0 nM 7.38
CHEMBL1863061 FLURTAMONE IC50 = 47.0 nM 7.33
CHEMBL1881194 NORFLURAZONE IC50 = 330.0 nM 6.48
CHEMBL2286103 IC50 = 740.0 nM 6.13
CHEMBL2286102 IC50 = 1300.0 nM 5.89
CHEMBL2272974 IC50 = 4500.0 nM 5.35
CHEMBL232801 AMITROLE IC50 = 68000.0 nM 4.17