Assay Detail
Functional
CHEMBL3096672
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human DU145 cells by clonogenic assay
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | DU-145 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Nicotinamide phosphoribosyltransferase inhibitors, design, preparation, and structure-activity relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.19 | 8.19 |
| Inhibition | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3094257 | — | — | 1 | 8.19 |
| CHEMBL566757 | DAPORINAD | 2.0 | 1 | - |
| CHEMBL3094255 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3094257 | — | IC50 | = | 6.39 | nM | 8.19 |
| CHEMBL566757 | DAPORINAD | Inhibition | - | % | - | |
| CHEMBL3094255 | — | IC50 | > | 50.0 | nM | - |