Assay Detail
ADMET
CHEMBL3096912
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of CYP3A4 (unknown origin) using 7-benzyloxy-4-trifluoromethylcoumarin as substrate
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Function-regulating pharmacophores in a sulfonamide class of glucocorticoid receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.84 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3093461 | — | — | 1 | 6.24 |
| CHEMBL3093462 | — | — | 1 | 6.03 |
| CHEMBL3093463 | — | — | 1 | 5.24 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3093461 | — | IC50 | = | 570.0 | nM | 6.24 |
| CHEMBL3093462 | — | IC50 | = | 940.0 | nM | 6.03 |
| CHEMBL3093463 | — | IC50 | = | 5800.0 | nM | 5.24 |