Assay Detail
Binding
CHEMBL3097098
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]ketanserin from 5-HT2 receptor in rat brain after 120 mins by liquid scintillation counting analysis
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Chlorophenylpiperazine analogues as high affinity dopamine transporter ligands.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 6.36 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL113621 | — | — | 1 | 7.28 |
| CHEMBL112125 | — | — | 1 | 6.41 |
| CHEMBL3093268 | — | — | 1 | 6.32 |
| CHEMBL325262 | — | — | 1 | 6.30 |
| CHEMBL3093269 | — | — | 1 | 6.29 |
| CHEMBL3093270 | — | — | 1 | 6.02 |
| CHEMBL145867 | — | — | 1 | 5.91 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL113621 | — | Ki | = | 53.0 | nM | 7.28 |
| CHEMBL112125 | — | Ki | = | 391.0 | nM | 6.41 |
| CHEMBL3093268 | — | Ki | = | 484.0 | nM | 6.32 |
| CHEMBL325262 | — | Ki | = | 498.0 | nM | 6.30 |
| CHEMBL3093269 | — | Ki | = | 518.0 | nM | 6.29 |
| CHEMBL3093270 | — | Ki | = | 952.0 | nM | 6.02 |
| CHEMBL145867 | — | Ki | = | 1238.0 | nM | 5.91 |