Assay Detail
Functional
CHEMBL3101587
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Antiproliferative activity against human HeLa cells
10
Total Activities
10
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
NAD-based inhibitors with anticancer potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 10 | 5.22 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3098189 | — | — | 1 | 6.00 |
| CHEMBL3098190 | — | — | 1 | 5.52 |
| CHEMBL3098188 | — | — | 1 | 5.35 |
| CHEMBL410744 | — | — | 1 | 5.24 |
| CHEMBL392204 | — | — | 1 | 5.17 |
| CHEMBL3098192 | — | — | 1 | 4.96 |
| CHEMBL3098191 | — | — | 1 | 4.92 |
| CHEMBL3098178 | — | — | 1 | 4.60 |
| CHEMBL3098179 | — | — | 1 | - |
| CHEMBL3098177 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3098189 | — | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3098190 | — | IC50 | = | 3000.0 | nM | 5.52 |
| CHEMBL3098188 | — | IC50 | = | 4500.0 | nM | 5.35 |
| CHEMBL410744 | — | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL392204 | — | IC50 | = | 6700.0 | nM | 5.17 |
| CHEMBL3098192 | — | IC50 | = | 11000.0 | nM | 4.96 |
| CHEMBL3098191 | — | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL3098178 | — | IC50 | = | 25000.0 | nM | 4.60 |
| CHEMBL3098179 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL3098177 | — | IC50 | > | 100000.0 | nM | - |