Assay Detail
ADMET
CHEMBL3137403
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DNDI: CYP Inhibition
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
DNDi T. cruzi fenarimol series dataset from which preclinical candidate EPL-BS1246 was identified (see also related datasets CHEMBL2448688 and CHEMBL3137440)
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.93 | 5.18 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL3104488 | — | — | 1 | 5.18 |
| CHEMBL3104490 | — | — | 1 | 5.15 |
| CHEMBL3104376 | — | — | 1 | 4.70 |
| CHEMBL3104486 | — | — | 1 | 4.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL3104488 | — | IC50 | = | 6600.0 | nM | 5.18 |
| CHEMBL3104490 | — | IC50 | = | 7100.0 | nM | 5.15 |
| CHEMBL3104376 | — | IC50 | = | 20000.0 | nM | 4.70 |
| CHEMBL3104486 | — | IC50 | = | 20000.0 | nM | 4.70 |