Assay Detail
Binding
CHEMBL3222681
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]mibolerone from human AR expressed in COS cells after 3.5 hrs by liquid scintillation counting analysis
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | COS |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Probing androgen receptor co-factor selectivity profiles: a chemical tool to determine cross-talk between androgen receptor and -catenin in vivo
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 7.47 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL27769 | STANOLONE | 2.0 | 1 | 7.96 |
| CHEMBL1170 | TESTOSTERONE PROPIONATE | 4.0 | 1 | 7.75 |
| CHEMBL3221237 | MK-0773 | 2.0 | 1 | 6.71 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL27769 | STANOLONE | IC50 | = | 11.0 | nM | 7.96 |
| CHEMBL1170 | TESTOSTERONE PROPIONATE | IC50 | = | 18.0 | nM | 7.75 |
| CHEMBL3221237 | MK-0773 | IC50 | = | 196.0 | nM | 6.71 |