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Assay Detail

CHEMBL3225196

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against mouse P388 cells after 48 hrs by XTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Cell Type P388
Confidence 1 — Organism
Curated By Autocuration

Target

P388 (CHEMBL389)
Type CELL-LINE
Organism Mus musculus

Publication

Progress on lamellarins
Pla D, Albericio F, Alvarez M
Medchemcomm (2011) 2 : 689 -697
· DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 6 6.87 7.10

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL3218975 1 7.10
CHEMBL301226 1 7.10
CHEMBL373114 LAMELLARIN D 1 7.00
CHEMBL3218976 1 7.00
CHEMBL3218977 1 6.52
CHEMBL3218978 1 6.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL3218975 IC50 = 80.0 nM 7.10
CHEMBL301226 IC50 = 80.0 nM 7.10
CHEMBL373114 LAMELLARIN D IC50 = 100.0 nM 7.00
CHEMBL3218976 IC50 = 100.0 nM 7.00
CHEMBL3218977 IC50 = 300.0 nM 6.52
CHEMBL3218978 IC50 = 300.0 nM 6.52