Assay Detail
Functional
CHEMBL3242296
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Antibacterial activity against vancomycin-sensitive Enterococcus faecalis 12-5 after 18 hrs by broth microdilution method
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterococcus faecalis |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Spiromastixones A-O, antibacterial chlorodepsidones from a deep-sea-derived Spiromastix sp. fungus.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 8 | 4.98 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL5315124 | LEVOFLOXACIN | 4.0 | 1 | 6.00 |
| CHEMBL3234400 | — | — | 1 | 5.40 |
| CHEMBL3234398 | — | — | 1 | 4.80 |
| CHEMBL3234396 | — | — | 1 | 4.50 |
| CHEMBL3234399 | — | — | 1 | 4.19 |
| CHEMBL3234393 | — | — | 1 | - |
| CHEMBL3234395 | — | — | 1 | - |
| CHEMBL3234397 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL5315124 | LEVOFLOXACIN | IC50 | = | 1000.0 | nM | 6.00 |
| CHEMBL3234400 | — | IC50 | = | 4000.0 | nM | 5.40 |
| CHEMBL3234398 | — | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL3234396 | — | IC50 | = | 32000.0 | nM | 4.50 |
| CHEMBL3234399 | — | IC50 | = | 64000.0 | nM | 4.19 |
| CHEMBL3234393 | — | IC50 | > | 256000.0 | nM | - |
| CHEMBL3234395 | — | IC50 | > | 256000.0 | nM | - |
| CHEMBL3234397 | — | IC50 | > | 256000.0 | nM | - |