Assay Detail
Binding
CHEMBL3242684
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Mixed type inhibition of recombinant human DAO expressed in drosophila S2 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Cell Type | S2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Some non-conventional biomolecular targets for diamidines. A short survey.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 7.22 | 7.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL35241 | DIMINAZENE | 2.0 | 1 | 7.89 |
| CHEMBL55 | PENTAMIDINE | 4.0 | 1 | 6.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL35241 | DIMINAZENE | Ki | = | 13.0 | nM | 7.89 |
| CHEMBL55 | PENTAMIDINE | Ki | = | 290.0 | nM | 6.54 |