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Assay Detail

CHEMBL3267334

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Agonist activity at adenosine receptor A2a in isolated rat aorta assessed as efficacy
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Aorta
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Adenosine receptor A2a (CHEMBL302)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Adenosine A2A receptor as a drug discovery target.
de Lera Ruiz M, Lim YH, Zheng J.
J Med Chem (2014) 57 : 3623 -3650
PubMed 24164628 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.00 8.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL186113 GW-328267 1.0 1 8.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL186113 GW-328267 EC50 = 10.0 nM 8.00