Assay Detail
Functional
CHEMBL3267347
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at human recombinant adenosine receptor A2a by cAMP assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Adenosine A2A receptor as a drug discovery target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 8.42 | 10.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1095999 | — | — | 1 | 10.00 |
| CHEMBL1087189 | — | — | 1 | 8.39 |
| CHEMBL1095172 | — | — | 1 | 8.36 |
| CHEMBL3222062 | — | — | 1 | 8.28 |
| CHEMBL1095488 | — | — | 1 | 8.19 |
| CHEMBL3222061 | — | — | 1 | 8.18 |
| CHEMBL3222055 | — | — | 1 | 7.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1095999 | — | Ki | = | 0.1 | nM | 10.00 |
| CHEMBL1087189 | — | Ki | = | 4.1 | nM | 8.39 |
| CHEMBL1095172 | — | Ki | = | 4.4 | nM | 8.36 |
| CHEMBL3222062 | — | Ki | = | 5.3 | nM | 8.28 |
| CHEMBL1095488 | — | Ki | = | 6.5 | nM | 8.19 |
| CHEMBL3222061 | — | Ki | = | 6.6 | nM | 8.18 |
| CHEMBL3222055 | — | Ki | = | 29.0 | nM | 7.54 |